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[6N]METHYL ADENINE IN THE NUCLEAR DNA OF A EUCARYOTE, TETRAHYMENA PYRIFORMIS
| Content Provider | Scilit |
|---|---|
| Author | Gorovsky, Martin A. Hattman, Stanley Pleger, Gloria Lorick |
| Copyright Year | 1973 |
| Description | DNA isolated from macronuclei of the ciliate, Tetrahymena pyriformis, has been found to contain [6N]methyl adenine (MeAde); this represents the first clear demonstration of significant amounts of MeAde in the DNA of a eucaryote. The amounts of macronuclear MeAde differed slightly between different strains of Tetrahymena, with approximately 0.65–0.80% of the adenine bases being methylated. The MeAde content of macronuclear DNA did not seem to vary in different physiological states. The level of MeAde in DNA isolated from micronuclei, on the other hand, was quite low (at least tenfold lower than in macronuclear DNA). |
| Related Links | http://jcb.rupress.org/content/56/3/697.full.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108936/pdf |
| Ending Page | 701 |
| Page Count | 5 |
| Starting Page | 697 |
| DOI | 10.1083/jcb.56.3.697 |
| Journal | Journal of Cell Biology |
| Issue Number | 3 |
| Volume Number | 56 |
| Language | English |
| Publisher | Rockefeller University Press |
| Publisher Date | 1973-03-01 |
| Access Restriction | Open |
| Subject Keyword | Tetrahymena Methylated Eucaryote Pyriformis Dna Isolated Methyl Adenine Journal: Journal of Cell Biology (Vol- 56, Issue- 3) |
| Content Type | Text |