NDLI: A NEW MOUSE VIRUS CAUSING NECROSIS OF THE THYMUS IN NEWBORN MICE

Content Provider	Scilit
Author	Rowe, Wallace P. Capps, Worth I.
Copyright Year	1961
Description	A new mouse virus has been recovered from laboratory and wild mice. The agent induces a non-fatal disease in infant mice, characterized by acute massive necrosis of the thymic medulla and cortex, granulomatous reaction, and subsequent restoration of essentially normal architecture with scarring. Intranuclear inclusion bodies are produced. Virus may persist in tissues of convalescent mice for many months. Electron micrographs of acutely infected thymuses showed nuclear and cytoplasmic karyoannular particles and masses of parallel fibrils in nuclei.
Related Links	http://jem.rupress.org/content/113/5/831.full.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137417/pdf
Ending Page	844
Page Count	14
Starting Page	831
DOI	10.1084/jem.113.5.831
Journal	The Journal of experimental medicine
Issue Number	5
Volume Number	113
Language	English
Publisher	Rockefeller University Press
Publisher Date	1961-05-01
Access Restriction	Open
Subject Keyword	Peripheral Vascular Disease Urology and Nephrology Life History Pathology Serology Virus Journal: The Journal of experimental medicine (Vol- 113, Issue- 5)
Content Type	Text

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