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Evaluation of antimicrobial effect of Malaysian geopropolis with Aloe vera against Enterococcus faecalis to be used as an intracanal medicament in endodontics
| Content Provider | Scilit |
|---|---|
| Author | Ismail, Ikmal Hisham Yusof, Eleena Mohd Hamka, Farah Aminah Azmi, Nur Amirah Khan, Hasnah Begum Said Gulam Al-Bayaty, Fouad Hussain |
| Copyright Year | 2020 |
| Abstract | Introduction: Enterococcus faecalis can be found in failed endodontic treatment (FET) even after performing primary endodontic treatment (PET). Calcium hydroxide $(Ca(OH)_{2}$) cannot fully eliminate this microorganism during PET. Brazilian green propolis (bee glue) was found to be more effective against E. faecalis when compared to $Ca(OH)_{2}$. A much less studied Malaysian geopropolis (MP) as well as Aloe vera (AV) is antibacterial but is unknown against E. faecalis. Objective: The objective of this study is to determine the antimicrobial effects of MP, AV, and MP + AV in comparison with $Ca(OH)_{2}$ against E. faecalis, as an intracanal medicament. Materials and Methods: Antimicrobial activity of MP, AV, MP + AV, $Ca(OH)_{2}$, and dimethyl sulfoxide was tested against E. faecalis using antimicrobial sensitivity testing, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC). The results were analyzed by Kruskal–Wallis test with Mann–Whitney post hoc test and repeated measures analysis of variance with Bonferroni post hoc test (P < 0.05). Results: For agar well-diffusion method, MP + AV gave maximum inhibition zone diameter (mean: 8.11 ± 0.015 mm), MP (mean: 6.21 ± 0.046 mm, $Ca(OH)_{2}$ (mean: 5.5 ± 0.006), and AV (mean: 5.05 ± 0.012) with P < 0.05. MIC for MP + AV was 2 mg/ml, MP at 8 mg/ml, $Ca(OH)_{2}$ at 8 mg/ml, and AV at 16 mg/ml. The MBC for MP + AV is at 4 mg/ml, MP at 16 mg/ml, $Ca(OH)_{2}$ at 16 mg/ml, and AV at 32 mg/ml. Conclusion: The combination of MP and AV consistently showed better antimicrobial activity compared to MP and AV alone against E. faecalis. The findings suggest that MP and AV used in combination may be an ideal intracanal medicament in FET and PET. |
| Related Links | https://www.jcd.org.in/article.asp?issn=0972-0707;year=2020;volume=23;issue=5;spage=489;epage=496;aulast=Ismail;type=2 |
| Ending Page | 496 |
| Page Count | 8 |
| Starting Page | 489 |
| File Format | XHTML |
| ISSN | 09720707 |
| e-ISSN | 09745203 |
| DOI | 10.4103/jcd.jcd_528_20 |
| Journal | Journal of Conservative Dentistry : Jcd |
| Issue Number | 5 |
| Volume Number | 23 |
| Language | English |
| Publisher | Medknow |
| Publisher Date | 2020-01-01 |
| Access Restriction | Open |
| Subject Keyword | Integrative and Complementary Medicine Aloe Vera Antimicrobial Enterococcus Faecalis Intracanal Medicament Malaysian Geopropolis Journal of Conservative Dentistry : Jcd, Volume 23, Issue 5 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Dentistry |
