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The Most Important Predictors of Metabolic Syndrome Persistence after 10-year Follow-Up: YHHP Study.
| Content Provider | Scilit |
|---|---|
| Author | Hassanabadi, Mohammadtaghi Sareban Mirhosseini, Seyed Jalil Mirzaei, Masoud Namayandeh, Seyedeh Mahdieh Gannar, Fadoua Boffetta, Paolo Ahmadi, Nastaran Kazeminasab, Mahmood Abargouei, Amin Salehi- Beiki, Omid Pakseresht, Mohammadreza Tabesh, Maryam |
| Copyright Year | 2020 |
| Abstract | Background: Metabolic syndrome (MetS) is one of the world's largest health epidemics, and its management is a major challenge worldwide. The aim of this 10-year follow-up study was to assess the most important predictors of MetS persistence among an Iranian adult population. Methods: In this cohort study, 887 out of 2000 participants with MetS aged 20–74 years in the central part of Iran were followed-up for about 10 years from 2005–2006 to 2015–2016. MetS was defined based on the criteria of NCEP-ATP III adopted for the Iranian population. Cox proportional hazards regression was conducted to evaluate the predictors of MetS persistence in crude- and multivariate-adjusted models. Results: Our analyses showed that 648 out of 887 participants (73%) completed the follow-up and 565 (87.2%) of them had persistence of MetS after 10-year follow-up. There was a significant association between age, weight, body mass index, triglyceride, and waist circumference in participants who had MetS compared to those without MetS after 10-year follow-up (P < 0.05). There was a direct association between increases in the mean changes of systolic/diastolic blood pressure, waist circumference, and low HDL-C and risk of MetS persistence after adjusting the model for sex and age in the total population $(P_{trend}P_{trend}$= 0.001). Conclusions: Most of the risk factors of MetS were positively associated with persistence of MetS. Therefore, modification of lifestyle is recommended to reduce MetS. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187548/pdf http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2020;volume=11;issue=1;spage=33;epage=33;aulast=Sareban;type=2 |
| File Format | XHTML |
| ISSN | 20087802 |
| DOI | 10.4103/ijpvm.IJPVM_215_18 |
| Journal | International Journal of Preventive Medicine |
| Issue Number | 1 |
| Volume Number | 11 |
| Language | English |
| Publisher | Medknow |
| Access Restriction | Open |
| Subject Keyword | Endocrinology and Metabolism Cohort Studies Metabolic Syndrome Persistence International Journal of Preventive Medicine, Volume 11, Issue 1 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Public Health, Environmental and Occupational Health |
