NDLI: Targeting IL-23: Insights into the pathogenesis and the treatment of psoriasis

Content Provider	Scilit
Author	Lima, Hermenio Cavalcante Kimball, Alexandra Boer
Copyright Year	2010
Abstract	Therapeutic experience strongly supports the use of TNF antagonists as important modalities in the treatment of psoriatic arthritis and plaque psoriasis. Studies with anti-IL-12/23 therapeutic agents, which act in different steps of the psoriatic inflammatory cascade, have also shown demonstrable efficacy. Here, we discuss this approach and its potential within the armamentarium for the treatment of psoriasis. Evidences that the selective blocking of IL-23 may be effective and safe therapy are also addressed.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887523/pdf http://www.e-ijd.org/article.asp?issn=0019-5154;year=2010;volume=55;issue=2;spage=171;epage=175;aulast=Lima;type=2
File Format	XHTML
ISSN	00195154
e-ISSN	19983611
DOI	10.4103/0019-5154.62760
Journal	Indian Journal of Dermatology
Issue Number	2
Volume Number	55
Language	English
Publisher	Medknow
Access Restriction	Open
Subject Keyword	Anti-il-12/23 Biological Treatment Il-12 Il-17 Il-23 Psoriasis Indian Journal of Dermatology, Volume 55, Issue 2
Content Type	Text
Resource Type	Article
Subject	Dermatology

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