Different regenerative responses of two platelet concentrates in the treatment of human periodontal infrabony defects: A clinico-radiographic study

Content Provider	Scilit
Author	Bhattacharya, Hirak S. Upadhyay, Himani Manjunath, R. G. Shiva Agarwal, Ashutosh Upadhyay, Himanshu Agarwal, Manvi Chandra
Copyright Year	2020
Abstract	Background: Platelet concentrates usage in the treatment of intrabony defects has been improved due to advancement of research. Many generation of platelet concentrates were used, but research regarding advanced platelet-rich fibrin (A-PRF) regarding periodontal treatment is scanty. Aim: The purpose of the study was to evaluate and compare PRF and A-PRF in the treatment of human periodontal infrabony defects (IBDs) both clinically and radiographically. Materials and Methods: Twenty- eight patients having IBDs were divided into Group A (PRF) and Group B (A-PRF). Clinical parameters such as plaque index, gingival index, probing pocket depth (PPD), and clinical attachment level (CAL) were recorded at baseline and 3 and 6 months and radiographic examination at baseline and 6 months were also recorded to evaluate defect fill, resolution, and change in the alveolar crest height. Then, all the data were tabulated in a Microsoft Excel sheet and subjected to statistical analysis. Mean and standard deviations of the clinical and radiographic parameters were calculated, and unpaired t-test was performed to assess intergroup comparison at different time intervals. Results: Intragroup comparison showed statistically significant improvement in PPD and CAL at 3 and 6 months while statistically significant improvement was observed in mean defect fill and resolution in Group B. Conclusion: Individually, both the materials have shown promising results. However, statistically, PRF group (Group A) showed better treatment outcome in terms of bone fill and A-PRF group (Group B) in terms of soft tissue healing.
Related Links	https://www.contempclindent.org/article.asp?issn=0976-237X;year=2020;volume=11;issue=3;spage=217;epage=222;aulast=Upadhyay;type=2
Ending Page	222
Page Count	6
Starting Page	217
File Format	XHTML
ISSN	0976237X
e-ISSN	09762361
DOI	10.4103/ccd.ccd_7_19
Journal	Contemporary Clinical Dentistry
Issue Number	3
Volume Number	11
Language	English
Publisher	Medknow
Publisher Date	2020-01-01
Access Restriction	Open
Subject Keyword	Dentistry and Oral Surgery Advanced Platelet-rich Fibrin Infrabony Defect Periodontal Regeneration Platelet-rich Fibrin Contemporary Clinical Dentistry, Volume 11, Issue 3
Content Type	Text
Resource Type	Article
Subject	Oral Surgery Periodontics Orthodontics