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In vitro evaluation of antimicrobial and antioxidant activities of methanolic extract of Jasminum humile Leaves

Content Provider	Scilit
Author	Kumar, Ashok Nain, Jaspreet Nain, Parminder Sharma, Sunil
Copyright Year	2011
Abstract	ObjectiveTo evaluate in vitro antimicrobial and antioxidant activities of methanolic extract of Jasminum humile (J. humile) leaves extract.MethodMethanolic extract of J. humile was evaluated for its antimicrobial activity by using agar well diffusion method & their possible antioxidant assay by two complementary test systems, namely DPPH and hydrogen peroxide scavenging activity. These various antioxidant activities were compared to standard antioxidants such as ascorbic acid for both the tests.ResultsIn the DPPH & hydrogen peroxide scavenging activity, the IC50 value of methanol extract was 70.43 μg/mL & 60.79 μg/mL respectively. Further, the extract showed inhibitory activity for Gram-positive and negative bacteria at different concentrations. The maximum antibacterial activity of extract was exhibited against Staphylococcus aureus (S. aureus) at concentration 50 mg/mL when compared with ciprofloxacinConclusionsThese results clearly indicate that J. humile is effective in scavenging free radicals and has the potential to be a powerful antioxidant. Thus, the results obtained in the present study indicate that J. humile leaves extract could be considered as a potential source of natural antioxidants and that could be used as an effective source against bacterial diseases
Related Links	https://core.ac.uk/download/pdf/82586926.pdf
Ending Page	807
Page Count	4
Starting Page	804
File Format	XHTML
ISSN	19957645
e-ISSN	23524146
DOI	10.1016/s1995-7645(11)60198-3
Journal	Asian Pacific Journal of Tropical Medicine
Issue Number	10
Volume Number	4
Language	English
Publisher	Medknow
Access Restriction	Open
Subject Keyword	Integrative and Complementary Medicine Methanolic Extract Antioxidant Leaves Extract Aureus Humile Jasminum Asian Pacific Journal of Tropical Medicine, Volume 4, Issue 10
Content Type	Text
Resource Type	Article
Subject	Medicine

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