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The accuracy of transcutaneous bilirubin measurements in preterm infants
| Content Provider | Scilit |
|---|---|
| Author | Alsafadi, Tariq Rushdi Mohieldeen Alsaedi, Saad Abdullah |
| Copyright Year | 2015 |
| Abstract | Context: Jaundice is common in preterm infants and requires frequent blood sampling for total serum bilirubin (TSB) measurements. Transcutaneous bilirubin (TcB) measurement is a noninvasive method to determine TSB, although its accuracy is less conclusive in preterm than in term infants. Aims: The aim was to determine the correlation and agreement between TcB and TSB in jaundiced Saudi preterm infants. Settings and Design: Design - Prospective study. Setting - Neonatal intensive care unit at a tertiary university hospital. Subjects and Methods: Jaundiced preterm infants 24-36 weeks gestational age (GA). JM-103 device and direct spectrometry were used to measure TcB and TSB, respectively. TcB measurements were obtained at the forehead ± 15 min of blood sampling for TSB for every clinically jaundiced preterm infant. Statistical analysis used: The correlations (r) of TcB-TSB values were performed by Pearson linear regression. The bias and 95% limits of agreement were analyzed using Bland-Altman method. Results: A total of 152 paired TcB-TSB readings for 91 jaundiced preterm infants were obtained. Mean birth weight (BW) ± standard deviation was 1690 ± 500 g, mean GA was 32.2 ± 3.1 weeks, mean postnatal age was 62 ± 40 h, (r) were 0.78 and 0.88 and 0.87 for all the preterm infants and ≤ 32 weeks and very low BW, respectively. The bias was 16.6 μmol/L, 95% limit of agreement was (−46.3-79.9 μmol/L). Conclusions: JM-103 device is effective in estimation of TSB. The correlation is inversely proportional to BW < 1500 g and GA ≤ 32 weeks. It tends to mildly overestimates bilirubin values, which make it safe. Its use can reduce blood sampling. |
| Related Links | https://www.jcnonweb.com/article.asp?issn=2249-4847;year=2015;volume=4;issue=1;spage=18;epage=21;aulast=Alsafadi;type=2 |
| File Format | XHTML |
| ISSN | 22494847 |
| DOI | 10.4103/2249-4847.151160 |
| Journal | Journal of Clinical Neonatology |
| Issue Number | 1 |
| Volume Number | 4 |
| Language | English |
| Publisher | Medknow |
| Publisher Date | 2015-01-01 |
| Access Restriction | Open |
| Subject Keyword | Jm-103 Device Preterm Infants Total Serum Bilirubin Transcutaneous Bilirubin Journal of Clinical Neonatology, Volume 4, Issue 1 |
| Content Type | Text |
| Resource Type | Article |
