Papillary thyroid carcinoma with nodular fasciitis-like stroma: A rare variant with distinctive morphology

Content Provider	Scilit
Author	Mardi, Kavita
Copyright Year	2017
Abstract	Papillary thyroid carcinoma (PTC) is a common malignancy with multiple variants, some of which are rarely encountered in routine surgical pathology practice. PTC with exuberant nodular fasciitis-like stroma or PTC with fibromatosis-like stroma is one such variant. This tumor is characterized by an abundant stromal component with an intervening epithelial component with the typical morphologic features of PTC. We describe gross and histopathological features of this rare variant of papillary carcinoma in a 38-year-old female and review the literature. We also discuss the importance of a thorough search for epithelial components within any fibroproliferative lesion of the thyroid and address the diagnostic difficulties created by the tumor's extensive stromal component. Given the rarity of this condition, the experience gained from the present case is a useful addition to the current knowledge on disease prognostication and management.
Related Links	http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2017;volume=60;issue=3;spage=390;epage=392;aulast=Mardi;type=2
Ending Page	392
Page Count	3
Starting Page	390
File Format	XHTML
ISSN	03774929
e-ISSN	19362625
DOI	10.4103/ijpm.ijpm_832_15
Journal	Indian Journal of Pathology and Microbiology
Issue Number	3
Volume Number	60
Language	English
Publisher	Medknow
Access Restriction	Open
Subject Keyword	Dermatology Nodular Fasciitis-like Stroma Papillary Carcinoma Thyroid Indian Journal of Pathology and Microbiology, Volume 60, Issue 3
Content Type	Text
Resource Type	Article
Subject	Pathology and Forensic Medicine Microbiology (medical)