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Oral microbial shift following 1-month supplementation of probiotic chewable tablets containing Lactobacillus reuteri UBLRu-87 as an adjunct to phase 1 periodontal therapy in chronic periodontitis patients: A randomized controlled clinical trial
| Content Provider | Scilit |
|---|---|
| Author | Nisha, Kj Jebin, A. Aysha Padmanabhan, Shyam |
| Copyright Year | 2021 |
| Abstract | Context: Although Lactobacilli as a probiotic was established as a treatment for a wide range of systemic infections, its role in periodontitis and oral microbiota is still under investigation. Aims: The present randomized clinical trial was aimed to evaluate the effects of probiotic chewable tablets containing Lactobacillus reuteri UBLRu-87 along with initial periodontal therapy on clinical parameters and oral microbiota of chronic periodontitis (CP) patients. Settings and Design: The randomized controlled clinical trial. Subjects and Methods: Thirty CP patients were selected who received scaling and root planing (SRP) and were randomly allocated into two treatment groups; Groups A and B. Group A received L. reuteri-containing chewable probiotic tablets. The clinical parameters (plaque index, gingival index, probing pocket depth, clinical attachment level), and microbiological parameters (Porphyromonas gingivalis and L. reuteri levels using real-time polymerase chain reaction) were evaluated at baseline, following treatment at 1 month and 3 months in both groups. Statistical Analysis: Paired t-test and unpaired t-test were used for the statistical analysis. Results: On intergroup analysis, statistically significant improvement in clinical as well as microbiological parameters was observed in Group A (SRP + PROBIOTIC) compared to Group B (SRP ALONE) at all evaluation time points. Conclusion: Probiotic chewable tablets containing L. reuteri may be a useful adjunct along with initial periodontal therapy to slow recolonization of periopathogens along with improvement in clinical outcomes of CP. Further long-term trials are necessary to establish the optimal dosage of probiotics. |
| Related Links | https://www.contempclindent.org/article.asp?issn=0976-237X;year=2021;volume=12;issue=2;spage=121;epage=127;aulast=Jebin;type=2 |
| Ending Page | 127 |
| Page Count | 7 |
| Starting Page | 121 |
| File Format | XHTML |
| ISSN | 0976237X |
| e-ISSN | 09762361 |
| DOI | 10.4103/ccd.ccd_135_20 |
| Journal | Contemporary Clinical Dentistry |
| Issue Number | 2 |
| Volume Number | 12 |
| Language | English |
| Publisher | Medknow |
| Access Restriction | Open |
| Subject Keyword | Dentistry and Oral Surgery Chronic Periodontitis Lactobacillus Reuteri Probiotics Root Planing Contemporary Clinical Dentistry, Volume 12, Issue 2 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Oral Surgery Periodontics Orthodontics |
