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Postperfusion lung syndrome: Respiratory mechanics, respiratory indices and biomarkers
| Content Provider | Scilit |
|---|---|
| Author | Yuan, Shi-Min |
| Copyright Year | 2015 |
| Abstract | Postperfusion lung syndrome is rare but lethal. Secondary inflammatory response was the popularly accepted theory for the underlying etiology. Respiratory index (RI) and arterial oxygen tension/fractional inspired oxygen can be reliable indices for the diagnosis of this syndrome as X-ray appearance is always insignificant at the early stage of the onset. Evaluations of extravascular lung water content and pulmonary compliance are also helpful in the definite diagnosis. Multiorgan failure and triple acid-base disturbances that might develop secondary to postperfusion lung syndrome are responsible for the poor prognosis and increased mortality rather than postperfusion lung syndrome itself. Mechanical ventilation with low tidal volume (TV) and proper positive end-expiratory pressure can be an effective treatment strategy. Use of ulinastatin and propofol may benefit the patients through different mechanisms. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518344/pdf |
| Ending Page | 157 |
| Page Count | 7 |
| Starting Page | 151 |
| File Format | XHTML |
| ISSN | 18171737 |
| e-ISSN | 19983557 |
| DOI | 10.4103/1817-1737.150736 |
| Journal | Annals of Thoracic Medicine |
| Issue Number | 3 |
| Volume Number | 10 |
| Language | English |
| Publisher | Medknow |
| Access Restriction | Open |
| Subject Keyword | Medical Laboratory Technology Acid-base Imbalance Cardiopulmonary Bypass Mechanical Ventilators Multiple Organ Failure Respiratory Insufficiency Annals of Thoracic Medicine, Volume 10, Issue 3 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pulmonary and Respiratory Medicine Surgery Cardiology and Cardiovascular Medicine |
