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The effect of multimodal analgesia on intraoperative morphine requirement in lumbar spine surgeries
| Content Provider | Scilit |
|---|---|
| Author | Savitha, Keelara Shivalingaiah Dhanpal, Radhika Kothari, Apoorwa N. |
| Copyright Year | 2017 |
| Abstract | Background: Lumbar spine surgery demands intense analgesia. Preemptive multimodal analgesia (MMA) is a novel approach to attenuate the stress response to surgical stimulus. Aims: The aim of the study was to assess the intraoperative morphine consumption in patients undergoing lumbar spine surgery. Patients and Methods: A randomized, prospective, double-blind study involving 42 patients belonging to the American Society of Anesthesiologists Class I and II scheduled to undergo elective lumbar spine surgery were allocated into two groups of 21 each. Group A (study group) received injection diclofenac sodium, paracetamol, clonidine, and skin infiltration with bupivacaine adrenaline and Group B (control group) received paracetamol and skin infiltration with saline adrenaline. Preemptive analgesia was practiced in both the groups. Intraoperative morphine consumption was documented. Statistical Methods: Intraoperative morphine consumption between the two groups was compared using Mann–Whitney U-test. Postextubation sedation score between the two groups was compared using Chi-square test and presented as number and percentage. P < 5% was considered statistically significant. Results: Intraoperative morphine consumption was significantly low in the study group (P < 0.001). Postextubation sedation score was comparable between the two groups. Conclusion: Preemptive MMA has demonstrated significant morphine sparing effect intraoperatively in patients undergoing lumbar spine surgeries. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490130/pdf |
| Ending Page | 400 |
| Page Count | 4 |
| Starting Page | 397 |
| File Format | XHTML |
| ISSN | 02591162 |
| e-ISSN | 22297685 |
| DOI | 10.4103/0259-1162.194553 |
| Journal | Anesthesia: Essays and Researches |
| Issue Number | 2 |
| Volume Number | 11 |
| Language | English |
| Publisher | Medknow |
| Publisher Date | 2017-01-01 |
| Access Restriction | Open |
| Subject Keyword | Anesthesiology Bispectral Index Hemodynamic Parameters Lumbar Spine Surgery Morphine Multimodal Analgesia Preemptive Analgesia Anesthesia: Essays and Researches, Volume 11, Issue 2 |
| Content Type | Text |
| Resource Type | Article |
