Loading...
Please wait, while we are loading the content...
Similar Documents
Co-infection of herpes simplex virus Type 2 and HIV infections among pregnant women in Ibadan, Nigeria
| Content Provider | Scilit |
|---|---|
| Author | Ajani, TinuadeAdesola Anaedobe, ChinenyeGloria |
| Copyright Year | 2019 |
| Abstract | Genital infection with herpes simplex virus type 2 (HSV-2) facilitates the acquisition of HIV, both mutually reinforcing infection. Lifelong latent HSV-2 infection raises concerns among women of reproductive age, considering the risk of neonatal transmission. In Nigeria, screening for HSV-2 and co-infection with HIV in antenatal clinics is not routine. This study was undertaken to determine the seroprevalence and co-infection of HSV-2 and HIV among pregnant women. This was a cross-sectional study conducted at the antenatal clinic of the University College Hospital, Ibadan, between March and August 2013. A total of 270 consenting pregnant women were enrolled. The study involved collecting socio-demographic data and laboratory determination of HSV-2 immunoglobulin G (IgG) and HIV seroprevalence using type-specific third-generation enzyme-linked immunosorbent assay (DIAPRO Diagnostic Bioprobes, Milan, Italy) and Uni-Gold Recombigen/ALERE determine, respectively. Data analyses were done using SPSS version 20 (SPSS Inc., IL, USA). The seroprevalence for HSV-2 type-specific IgG was 33.3% (90/270), and HIV antibodies were identified in 19.63% (53/270) of the women. The HIV co-infection was 38.8% (35/90) among HSV-2-positive women and 10% (18/180) among HSV-2-negative women. Majority of the HSV-2 positive women (62.2%, 56/90) presented in their 2nd trimester while 18.9% (17/90) in their 3rd trimester. The seroprevalence of HSV-2 in this pregnant population is lower than what is observed in some other Sub-Saharan African countries; however, HSV-2/HIV co-infection is high. The HSV-2-seronegative women are still susceptible to primary HSV-2 infection in pregnancy with increased risk for HIV co-infection and neonatal transmission. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380096/pdf |
| Ending Page | 24 |
| Page Count | 6 |
| Starting Page | 19 |
| File Format | XHTML |
| ISSN | 0974777X |
| e-ISSN | 09748245 |
| DOI | 10.4103/jgid.jgid_56_18 |
| Journal | Journal of Global Infectious Diseases |
| Issue Number | 1 |
| Volume Number | 11 |
| Language | English |
| Publisher | Medknow |
| Access Restriction | Open |
| Subject Keyword | Virology Herpes Simplex Virus Type 2 Neonatal Transmission Pregnancy Prevalence Journal of Global Infectious Diseases, Volume 11, Issue 1 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases |
