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A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma
| Content Provider | Scilit |
|---|---|
| Author | Addenan, Maftuhim May, Choo May Hooi, Teoh Kean Ismail, Fazliana Kamalden, Tengku Ain |
| Copyright Year | 2018 |
| Abstract | Langerhans cell histiocytosis (LCH) is rarely encountered in ophthalmology practice. It is a spectrum of disorder characterized by accumulation of histiocytes in various tissues. Diagnosis is challenging as it may simulate periorbital hematoma, rhabdomyosarcoma, and neuroblastoma. We report a case of unifocal LCH with orbital extension. Diagnosis was obtained from incisional biopsy, and histopathological examination showed numerous histiocytes with eosinophilic infiltrations. The presence of Langerhans cells was confirmed by the presence of protein S-100, CD1a, and/or Langerin (CD207). Treatment depends on the degree of organ involvement. She responded well to cytotoxic drugs and steroids. This emphasized that prompt tissue diagnosis is crucial for early management. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219334/pdf |
| Ending Page | 287 |
| Page Count | 4 |
| Starting Page | 284 |
| File Format | XHTML |
| ISSN | 0974620X |
| e-ISSN | 09747842 |
| DOI | 10.4103/ojo.OJO_149_2017 |
| Journal | Oman Journal of Ophthalmology |
| Issue Number | 3 |
| Volume Number | 11 |
| Language | English |
| Publisher | Medknow |
| Access Restriction | Open |
| Subject Keyword | Dermatology Langerhans Cell Histiocytosis Orbit Uniforcal Oman Journal of Ophthalmology, Volume 11, Issue 3 |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology |
