NDLI: Clinical predictors of acute kidney injury following snake bite envenomation

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Clinical predictors of acute kidney injury following snake bite envenomation

Content Provider	Scilit
Author	Patil, Tushar Deshpande, Archana S. Gulhane, Ragini V. Patil, Mangesh B. Dharod, Mrudul V. Bansod, Yogendra V.
Copyright Year	2013
Abstract	Background: Snake bite envenomation is a major public health concern in developing countries. Acute kidney injury (AKI) is as important cause of mortality in patients with vasculotoxic snake bite. Aims: This study was to evaluate the clinical profile of snake bite patients and to determine the predictors of developing AKI following snake bite. Materials and Methods: Two hundred and eighty-one patients with snake envenomation were included. Eighty-seven patients developed AKI (Group A) and 194 (Group B) did not. History, examination findings and investigations results were recorded and compared between the two groups. Results: In group A, 61 (70.11%) patients were male and in group B, 117 (60.30%) patients were male. Out of 281 patients, 232 had cellulitis, 113 had bleeding tendencies, 87 had oliguria, 76 had neuroparalysis, and 23 had hypotension at presentation. After multivariate analysis, bite to hospital time (P = 0.016), hypotension (P = 0.000), albuminuria (P = 0.000), bleeding time (P = 0.000), prothrombin time (P = 0.000), hemoglobin (P = 0.000) and total bilirubin (P = 0.010) were significant independent predictors of AKI. Conclusions: AKI developed in 30.96% of patients with snake bite, leading to mortality in 39.08% patients. Factors associated with AKI are bite to hospital time, hypotension, albuminuria, prolonged bleeding time, prolonged prothrombin time, low hemoglobin and a high total bilirubin.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842700/pdf http://www.najms.org/article.asp?issn=1947-2714;year=2013;volume=5;issue=10;spage=594;epage=599;aulast=Dharod;type=2
File Format	XHTML
ISSN	22501541
e-ISSN	19472714
DOI	10.4103/1947-2714.120795
Journal	North American Journal of Medical Sciences
Issue Number	10
Volume Number	5
Language	English
Publisher	Medknow
Access Restriction	Open
Subject Keyword	Integrative and Complementary Medicine Acute Kidney Injury Bite To Hospital Time Coagulopathy Envenomation Hemolysis Snake Bite North American Journal of Medical Sciences, Volume 5, Issue 10
Content Type	Text
Resource Type	Article
Subject	Medicine

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