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Preparation of a novel breviscapine-loaded halloysite nanotubes complex for controlled release of breviscapine
| Content Provider | Scilit |
|---|---|
| Author | Gao, Min Lu, Liqian Wang, Xiaoyue Lin, Houke Zhou, Qingsong |
| Copyright Year | 2017 |
| Description | Journal: Iop Conference Series: Materials Science and Engineering For sustain the release rate and prolong half-life of breviscapine in vivo, the breviscapine-loaded halloysite nanotubes complex was prepared. The breviscapine was encapsulated into halloysite nanotubes (HNTs) using a vacuum process. The complex were investigated by scanning electron microscopy (SEM), differential scanning calorimetry (DSC), transmission electron microscope (TEM), X-ray diffraction (XRD) and fourier transform infrared spectroscopy(FT-IR). The formation of breviscapine-loaded HNTs complex was proved by the test results of SEM, DSC, TEM and IR analysise. The results confirmed that breviscapine was successfully loaded in the halloysite nanotubes. Additionally, the in vitro drug release of breviscapine from breviscapine-loaded HNTs complex was investigated, the result indicated this complex has apparent sustained-release effect. |
| Related Links | http://iopscience.iop.org/article/10.1088/1757-899X/265/1/012011/pdf |
| ISSN | 17578981 |
| e-ISSN | 1757899X |
| DOI | 10.1088/1757-899x/265/1/012011 |
| Journal | Iop Conference Series: Materials Science and Engineering |
| Issue Number | 1 |
| Volume Number | 265 |
| Language | English |
| Publisher | IOP Publishing |
| Publisher Date | 2017-11-29 |
| Access Restriction | Open |
| Subject Keyword | Journal: Iop Conference Series: Materials Science and Engineering Loaded Halloysite Nanotubes Breviscapine Loaded Release of Breviscapine |
| Content Type | Text |
| Resource Type | Article |
