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Enhanced antibacterial activity of silver-decorated sandwich-like mesoporous silica/reduced graphene oxide nanosheets through photothermal effect
| Content Provider | Scilit |
|---|---|
| Author | Liu, Rong Wang, Xuandong Ye, Jun Xue, Ximei Zhang, Fangrong Zhang, Huicong Hou, Xuemei Liu, Xiaolong Zhang, Yun |
| Copyright Year | 2018 |
| Description | Journal: Nanotechnology Drug resistance of bacteria has become a global health problem, as it makes the conventional antibiotics less efficient. It is urgently needed to explore novel antibacterial materials and develop effective treatment strategies to overcome the drug resistance of antibiotics. Herein, we successfully synthesized silver decorated sandwich-like mesoporous silica/reduced graphene oxide nanosheets (rGO/MSN/Ag) as novel antibacterial material through facile method. The rGO and Ag nanoparticles can be reduced in the reaction system without adding any other reductants. In addition, the rGO/MSN/Ag showed higher photothermal conversion capacity due to the modification of silver nanoparticles and exhibited excellent antibacterial activities against P.putida, E.coli and Rhodococcus with relatively low dosage, which was confirmed by the minimum inhibitory concentration (MIC) test. Meanwhile, the E.coli with high concentration was selected for exposure with 808 nm laser, and the antibacterial effect was obviously enhanced by near-infrared irradiation induced photothermal effect. Moreover, the hepatocyte LO2 were used for cytotoxicity evaluation, and the rGO/MSN/Ag showed low toxicity and without detectable cytotoxicity at the antimicrobial dose. As the prepared rGO/MSN/Ag nanosheets have the advantages of low cost and high antibacterial activity, they might be of promising and useful antibacterial agents for different applications. |
| Related Links | http://iopscience.iop.org/article/10.1088/1361-6528/aaa624/pdf |
| ISSN | 09574484 |
| e-ISSN | 13616528 |
| DOI | 10.1088/1361-6528/aaa624 |
| Journal | Nanotechnology |
| Issue Number | 10 |
| Volume Number | 29 |
| Language | English |
| Publisher | IOP Publishing |
| Publisher Date | 2018-01-09 |
| Access Restriction | Open |
| Subject Keyword | Journal: Nanotechnology Antibacterial Activity Mesoporous Silica Photothermal Effect Reduced Graphene Oxide Silver Nanoparticle |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Nanoscience and Nanotechnology Mechanics of Materials Mechanical Engineering Bioengineering Electrical and Electronic Engineering |