NDLI: Noninvasive treatment efficacy monitoring and dose control for high-intensity focused ultrasound therapy using relative electrical impedance variation

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Noninvasive treatment efficacy monitoring and dose control for high-intensity focused ultrasound therapy using relative electrical impedance variation

Content Provider	Scilit
Author	GePu, Guo Su, Huidan Ma, Qingyu Tu, Juan Zhang, Dong
Copyright Year	2017
Description	Journal: Chinese Physics B As an effective therapeutic modality, high-intensity focused ultrasound (HIFU) can destroy tumour tissues by thermocoagulation with less metastasis, but it is still limited by inaccurate non-invasive temperature monitoring and efficacy evaluation. A model of electrical impedance measurement during HIFU therapy was established using the temperature-impedance relationship. Based on the simulations of acoustic pressure, temperature, and electrical conductivity, the impedance of the phantom was calculated and experimentally demonstrated for different values of acoustic power values and treatment time. We proved that the relative impedance variation (RIV) increases linearly with the increasing treatment time at a fixed acoustic power, and the relative impedance variation rate shows a linear relationship with the acoustic power. The RIV and treatment time required for HIFU treatment efficacy are inversely proportional to the acoustic power and the square of acoustic power, respectively. The favourable results suggest that RIV can be used as an efficient indicator for noninvasive temperature monitoring and efficacy evaluation and may provide new strategy for accurate dose control of HIFU therapy.
Related Links	http://iopscience.iop.org/article/10.1088/1674-1056/26/5/054302/pdf
ISSN	16741056
e-ISSN	20583834
DOI	10.1088/1674-1056/26/5/054302
Journal	Chinese Physics B
Issue Number	5
Volume Number	26
Language	English
Publisher	IOP Publishing
Publisher Date	2017-05-01
Access Restriction	Open
Subject Keyword	Journal: Chinese Physics B Acoustics and Ultrasonics Impedance Variation High Intensity Electrical Impedance Intensity Focused
Content Type	Text
Resource Type	Article
Subject	Physics and Astronomy

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