NDLI: The blanching process due to copper vapour laser treatment of port-wine stains

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The blanching process due to copper vapour laser treatment of port-wine stains

Content Provider	Scilit
Author	Mehrtens, Nathan W. Smithies, Derek J. Butler, Philip H. Walker, E. Peter
Copyright Year	1997
Description	Journal: Physics in Medicine & Biology We describe the causes and speed of transient blanching during copper vapour laser treatment of port-wine stains. Five watts of yellow (578 nm) light from a copper vapour laser was scanned over the lesion using a computer controlled scanning system. The clinical response of the lesion to treatment is transient blanching, followed immediately by erythema. The clinical response of sclerosed vessels is different in that an intravascular coagulum is observed. We measure the time taken for the lesion to blanch using two methods. First, high-speed photography is used to photograph the treatment process. Second, a photodiode measures the light re-emitted from the skin. Using illumination times of 3 to 5 ms and fluences of approximately , blanching times varied between 0 and 33 ms. We conclude that the cause of the transient blanching is not thermal denaturation of either collagen or epidermal melanin. Rather it is the rapid expulsion of red blood cells from the treated vessels. Our results have caused us to commence clinical trials using a new treatment protocol aimed at further improving the response of port-wine stains to copper vapour laser treatment.
Related Links	https://iopscience.iop.org/article/10.1088/0031-9155/42/6/001/pdf
ISSN	00319155
e-ISSN	13616560
DOI	10.1088/0031-9155/42/6/001
Journal	Physics in Medicine & Biology
Issue Number	6
Volume Number	42
Language	English
Publisher	IOP Publishing
Publisher Date	1997-06-01
Access Restriction	Open
Subject Keyword	Journal: Physics in Medicine & Biology Legal Medicine Copper Vapour Laser
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Radiological and Ultrasound Technology

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