NDLI: Gelatin sponge functionalized with gold/silver clusters for antibacterial application

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Gelatin sponge functionalized with gold/silver clusters for antibacterial application

Content Provider	Scilit
Author	Wang, Xiaoyu Guo, Jinjin Zhang, Qian Zhu, Shuxian Liu, Lu Jiang, Xiaofeng Wei, Da-Hua Liu, Ru-Shi Li, Lidong
Copyright Year	2019
Description	Journal: Nanotechnology Pathogenic bacterial infection, especially in the wound, may threaten human health. Developing new antibacterial materials for wound healing is still urgent. Metal nanoclusters have been explored as a novel antibacterial agent. Herein, biomolecule gelatin was chosen as a substrate and functionalized with gold/silver clusters for bacterial killing. Through a simple amidation reaction, gold/silver clusters were successfully conjugated in gelatin substrate to obtain Au/Ag@gelatin sponge. The presence of gold/silver clusters modified the porous structure of gelatin, and thus the water absorption and water retention of Au/Ag@gelatin sponge were enhanced. More importantly, the gold/silver clusters show aggregation-enhanced emission and strong reactive oxygen generation, that endow Au/Ag@gelatin sponge good antibacterial property. The good physical performance and favorable bactericidal activity of Au/Ag@gelatin sponge suggest their potential for applying as a wound dressing.
Related Links	https://iopscience.iop.org/article/10.1088/1361-6528/ab59eb/pdf
ISSN	09574484
e-ISSN	13616528
DOI	10.1088/1361-6528/ab59eb
Journal	Nanotechnology
Issue Number	13
Volume Number	31
Language	English
Publisher	IOP Publishing
Publisher Date	2019-11-21
Access Restriction	Open
Subject Keyword	Journal: Nanotechnology Gold/silver Clusters
Content Type	Text
Resource Type	Article
Subject	Chemistry Nanoscience and Nanotechnology Mechanics of Materials Mechanical Engineering Bioengineering Electrical and Electronic Engineering

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