Loading...
Please wait, while we are loading the content...
Similar Documents
A compact soft X-ray microscope using an electrode-less Z-pinch source
| Content Provider | Scilit |
|---|---|
| Author | Horne, S. F. Silterra, J. Holber, W. |
| Copyright Year | 2009 |
| Description | Journal: Journal of Physics: Conference Series Soft X-rays (< 1Kev) are of medical interest both for imaging and microdosimetry applications. X-ray sources at this low energy present a technological challenge. Synchrotrons, while very powerful and flexible, are enormously expensive national research facilities. Conventional X-ray sources based on electron bombardment can be compact and inexpensive, but low x-ray production efficiencies at low electron energies restrict this approach to very low power applications. Laser-based sources tend to be expensive and unreliable. Energetiq Technology, Inc. (Woburn, MA, USA) markets a 92 eV, 10W(2pi sr) electrode-less Z-pinch source developed for advanced semiconductor lithography. A modified version of this commercial product has produced 400 mW at 430 eV (2pi sr), appropriate for water window soft X-ray microscopy. The US NIH has funded Energetiq to design and construct a demonstration microscope using this source, coupled to a condenser optic, as the illumination system. The design of the condenser optic matches the unique characteristics of the source to the illumination requirements of the microscope, which is otherwise a conventional design. A separate program is underway to develop a microbeam system, in conjunction with the RARAF facility at Columbia University, NY, USA. The objective is to develop a focused, sub-micron beam capable of delivering > 1 Gy/second to the nucleus of a living cell. While most facilities of this type are coupled to a large and expensive particle accelerator, the Z-pinch X-ray source enables a compact, stand-alone design suitable to a small laboratory. The major technical issues in this system involve development of suitable focusing X-ray optics. Current status of these programs will be reported. (Supported by NIH grants 5R44RR022488-03 and 5R44RR023753-03) |
| Related Links | http://europepmc.org/articles/pmc2829841?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829841/pdf https://iopscience.iop.org/article/10.1088/1742-6596/186/1/012028/pdf |
| ISSN | 17426588 |
| e-ISSN | 17426596 |
| DOI | 10.1088/1742-6596/186/1/012028 |
| Journal | Journal of Physics: Conference Series |
| Issue Number | 1 |
| Volume Number | 186 |
| Language | English |
| Publisher | IOP Publishing |
| Publisher Date | 2009-09-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of Physics: Conference Series X Ray Sources Microscope Using Soft X Ray Z Pinch Source Electrode Less Z |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physics and Astronomy |
