NDLI: Exogenous imaging contrast and therapeutic agents for intravascular photoacoustic imaging and image-guided therapy

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Exogenous imaging contrast and therapeutic agents for intravascular photoacoustic imaging and image-guided therapy

Content Provider	Scilit
Author	Sowers, Timothy Wayne Emelianov, Stanislav Y.
Copyright Year	2018
Description	Journal: Physics in Medicine & Biology Intravascular photoacoustic imaging has been developed in recent years as a viable imaging modality for the assessment of atherosclerotic plaques. Exogenous imaging contrast and therapeutic agents further enhance this imaging modality and provide significant benefits. Imaging contrast agents can significantly increase photoacoustic signal, resulting in enhanced plaque detection and characterization. The ability to use these particles to molecularly target markers of disease progression makes it possible to determine patient specific levels of risk and plan treatments accordingly. With improved diagnosis, clinicians will be able to use therapeutic agents that are synergistic with intravascular photoacoustic imaging to treat atherosclerotic patients. Pre-clinical and clinical studies with relevance to intravascular photoacoustic imaging have shown promise in the area of diagnosis and therapeutics. In this review, we present a variety of imaging contrast agents that are either designed for or are compatible with intravascular photoacoustic imaging, cover uses of therapeutic agents that compliment this imaging modality, and discuss future directions of research in the field.
Related Links	http://iopscience.iop.org/article/10.1088/1361-6560/aae62b/pdf
ISSN	00319155
e-ISSN	13616560
DOI	10.1088/1361-6560/aae62b
Journal	Physics in Medicine & Biology
Issue Number	22
Volume Number	63
Language	English
Publisher	IOP Publishing
Publisher Date	2018-10-04
Access Restriction	Open
Subject Keyword	Journal: Physics in Medicine & Biology Pharmacology and Pharmacy Imaging Contrast Intravascular Photoacoustic Imaging
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Radiological and Ultrasound Technology

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