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$Fe^{3+}$-sensing by 3,3′,5,5′-tetramethylbenzidine-functionalized upconversion nanoparticles
| Content Provider | Scilit |
|---|---|
| Author | Meng, Zhipeng Wu, Suli Zhong, Linghua Sun, Xiaoqian Li, Lu Zhang, Shufen |
| Copyright Year | 2018 |
| Description | Journal: Nanotechnology Detection of Fe3+ ion is essential for human health, because it is an important element of hemoglobin to carry oxygen in the body of life. Here, a 3,3, '5,5'-tetramethylbenzidine (TMB) functionalized NaYF4: Yb3+, Er3+ composite upconversion probe, was developed and demonstrated Fe3+ sensing ability with high sensitivity and selectivity. The red emission of UCNPs has higher penetration depth in the tissu than green light and works within the biological window. The obtained hydrophobic NaYF4: Yb3+, Er3+ nanoparticles were treated by HCl to achieve hydrophilic ligand-free nanoparticles with non-saturated metal ions on their surface. Then, Fe3+ responsive TMB-UCNPs composite upconversion luminescence probe was formed through linking TMB onto the ligand-free UCNPs by coordination bond between NH2 groups in TMB and metal ions on UCNPs. Due to the efficient FRET from UCNPs to Fe3+-TMB, the obtained probe shows high sensitivity for detecting Fe3+ in the range of 0-100 μM with a detection limit of 0.217 μM. And the color change of detection system can also be recognized by the naked eye easily. The MTT experiments and the bioimaging experiments shows the promising prospect in the tissue imaging. |
| Related Links | http://iopscience.iop.org/article/10.1088/1361-6528/aafa34/pdf |
| ISSN | 09574484 |
| e-ISSN | 13616528 |
| DOI | 10.1088/1361-6528/aafa34 |
| Journal | Nanotechnology |
| Issue Number | 13 |
| Volume Number | 30 |
| Language | English |
| Publisher | IOP Publishing |
| Publisher Date | 2018-12-20 |
| Access Restriction | Open |
| Subject Keyword | Journal: Nanotechnology Fluorescent Sensor |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Nanoscience and Nanotechnology Mechanics of Materials Mechanical Engineering Bioengineering Electrical and Electronic Engineering |
