Fabrication and properties of a biodegradable β-TCP/Zn–Mg bio-composite

Content Provider	Scilit
Author	Guoliang, Lu Guangquan, Xu Bobo, Helian Li, Liang Debao, Liu
Copyright Year	2019
Description	Journal: Materials Research Express The good biocompatibility and moderate degradation rate of Zn-based alloys have attracted increasing attention in biodegradable biomaterials field. However, the unsatisfactory mechanical properties of pure zinc limited its biomedical applications. In this study, Zn-1Mg alloy and 1vol.%β-TCP/Zn-1Mg composite were fabricated using stirring casting assisted by ultrasonic vibration. Microstructure, mechanical properties, corrosion behavior and osteotoxicity of Zn-1Mg alloy and 1vol.%β-TCP/Zn-1Mg composite were tested and /evaluated. In comparison with the matrix alloy, the addition of 1vol.%β-TCP refined the grain size. The yield strength(YS), ultimate tensile strength(UTS) and elongation of the as-extruded composite were 249.3 MPa, 330.1 MPa, and 11.7% respectively, which increased by 10.2%, 9.9%, and 101.7% respectively. The corrosion rate of 1vol.%β-TCP/Zn-1Mg composite in SBF is 46 µm/a. Corrosion resistance of the composites was improved after ultrasonic treatment. The proliferation rate of MC3T3-E1 cell for Zn-1Mg alloy and 1vol.%β-TCP/Zn-1Mg composite extracts were above 80% after 1-5days in culture. As the culture time increased, the 1vol.%β-TCP/Zn-1Mg composite showed superior cytocompatibility compare to Zn-1Mg alloy.
Related Links	https://iopscience.iop.org/article/10.1088/2053-1591/ab2861/pdf
ISSN	20531591
e-ISSN	20531591
DOI	10.1088/2053-1591/ab2861
Journal	Materials Research Express
Issue Number	8
Volume Number	6
Language	English
Publisher	IOP Publishing
Publisher Date	2019-06-10
Access Restriction	Open
Subject Keyword	Journal: Materials Research Express
Content Type	Text
Resource Type	Article
Subject	Surfaces, Coatings and Films Metals and Alloys Biomaterials Electronic, Optical and Magnetic Materials Polymers and Plastics