Loading...
Please wait, while we are loading the content...
Similar Documents
Real-timein vivorectal wall dosimetry using plastic scintillation detectors for patients with prostate cancer
| Content Provider | Scilit |
|---|---|
| Author | Wootton, Landon Kudchadker, Rajat Lee, Andrew Beddar, Sam |
| Copyright Year | 2014 |
| Description | Journal: Physics in Medicine & Biology We designed and constructed an in vivo dosimetry system using plastic scintillation detectors (PSDs) to monitor dose to the rectal wall in patients undergoing intensity-modulated radiation therapy for prostate cancer. Five patients were enrolled in an Institutional Review Board-approved protocol for twice weekly in vivo dose monitoring with our system, resulting in a total of 142 in vivo dose measurements. PSDs were attached to the surface of endorectal balloons used for prostate immobilization to place the PSDs in contact with the rectal wall. Absorbed dose was measured in real time and the total measured dose was compared with the dose calculated by the treatment planning system on the daily computed tomographic image dataset. The mean difference between measured and calculated doses for the entire patient population was -0.4% (standard deviation 2.8%). The mean difference between daily measured and calculated doses for each patient ranged from -3.3% to 3.3% (standard deviation ranged from 5.6% to 7.1% for four patients and was 14.0% for the last, for whom optimal positioning of the detector was difficult owing to the patient's large size). Patients tolerated the detectors well and the treatment workflow was not compromised. Overall, PSDs performed well as in vivo dosimeters, providing excellent accuracy, real-time measurement and reusability. |
| Related Links | http://europepmc.org/articles/pmc3965908?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965908/pdf |
| Ending Page | 660 |
| Page Count | 14 |
| Starting Page | 647 |
| ISSN | 00319155 |
| e-ISSN | 13616560 |
| DOI | 10.1088/0031-9155/59/3/647 |
| Journal | Physics in Medicine & Biology |
| Issue Number | 3 |
| Volume Number | 59 |
| Language | English |
| Publisher | IOP Publishing |
| Publisher Date | 2014-01-17 |
| Access Restriction | Open |
| Subject Keyword | Journal: Physics in Medicine & Biology Radiology, Nuclear Medicine and Imaging Calculated Doses Measured Dose |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging Radiological and Ultrasound Technology |
