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Development and initial characterization of a high-resolution PET detector module with DOI
| Content Provider | Scilit |
|---|---|
| Author | Li, Mohan Wang, Yuli Abbaszadeh, Shiva |
| Copyright Year | 2020 |
| Description | Journal: Biomedical Physics & Engineering Express Organ-dedicated PET scanners are becoming more prevalent because of their advantages in higher sensitivity, improved image quality, and lower cost. Detectors utilized in these scanners have finer pixel size with depth of interaction (DOI) capability. This work presents a LYSO(Ce) detector module with DOI capability which has the potential to be scaled up to a high-resolution small animal or organ-dedicated PET system. For DOI capability, a submodule with one LYSO block detector utilizing PETsys TOFPET2 application-specific integrated circuit (ASIC) was previously developed in our lab. We scaled up the submodule and optimized the configuration to allow for a compact housing of the dual-readout boards in one side of the blocks by designing a high-speed dual-readout cable to maintain the original pin-to-pin relationship between the Samtec connectors. The module size is 53.8 × 57.8 $mm^{2}$. Each module has 2 × 2 LYSO blocks, each LYSO block consists of 4 × 4 LYSO units, and each LYSO unit contains a 6 × 6 array of 1 × 1 × 20 $mm^{3}$ LYSO crystals. The four lateral surfaces of LYSO crystal were mechanically ground to W14, and the two end surfaces were polished. Two ends of the LYSO crystal are optically connected to SiPM for DOI measurement. Eight LYSO blocks performance including energy, timing, and DOI resolution is characterized with a single LYSO slab. The in-panel and orthogonal-panel spatial resolution of the two modules with 107.4 mm distance between each other are measured at 9 positions within the field of view (FOV) with a$ ^{22}$Na source. Results show that the average energy, timing, and DOI resolution of all LYSO blocks are 16.13% ± 1.01% at 511 keV, 658.03 ± 15.18 ps, and 2.62 ± 0.06 mm, respectively. The energy and timing resolution of two modules are 16.35% and 0.86 ns, respectively. The in-panel and orthogonal-panel spatial resolution of the two modules at the FOV center are 1.9 and 4.4 mm respectively. |
| Related Links | https://iopscience.iop.org/article/10.1088/2057-1976/abbd4f/pdf |
| ISSN | 20571976 |
| e-ISSN | 20571976 |
| DOI | 10.1088/2057-1976/abbd4f |
| Journal | Biomedical Physics & Engineering Express |
| Issue Number | 6 |
| Volume Number | 6 |
| Language | English |
| Publisher | IOP Publishing |
| Publisher Date | 2020-10-14 |
| Access Restriction | Open |
| Subject Keyword | Journal: Biomedical Physics & Engineering Express Depth of Interaction Energy and Spatial Resolution Lutetium-yttrium Oxyorthosilicate (lyso) Positron Emission Tomography Silicon Photomultipliers (sipm) |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physiology Radiology, Nuclear Medicine and Imaging Biomaterials Biophysics Bioengineering Biomedical Engineering Health Informatics Computer Science Applications |
