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In vivofluorescence imaging for tissue diagnostics
| Content Provider | Scilit |
|---|---|
| Author | Andersson-Engels, Stefan Klinteberg, Claes Af Svanberg, K. |
| Copyright Year | 1997 |
| Description | Journal: Physics in Medicine & Biology Non-invasive fluorescence imaging has the potential to provide in vivo diagnostic information for many clinical specialities. Techniques have been developed over the years for simple ocular observations following UV excitation to sophisticated spectroscopic imaging using advanced equipment. Much of the impetus for research on fluorescence imaging for tissue diagnostics has come from parallel developments in photodynamic therapy of malignant lesions with fluorescent photosensitizers. However, the fluorescence of endogenous molecules (tissue autofluorescence) also plays an important role in most applications. In this paper, the possibilities of imaging tissues using fluorescence spectroscopy as a mean of tissue characterization are discussed. The various imaging techniques for extracting diagnostic information suggested in the literature are reviewed. The development of exogenous fluorophores for this purpose is also presented. Finally, the present status of clinical evaluation and future directions are discussed. |
| Related Links | https://lup.lub.lu.se/search/ws/files/5134374/2296979.pdf http://iopscience.iop.org/article/10.1088/0031-9155/42/5/006/pdf |
| Ending Page | 824 |
| Page Count | 10 |
| Starting Page | 815 |
| ISSN | 00319155 |
| e-ISSN | 13616560 |
| DOI | 10.1088/0031-9155/42/5/006 |
| Journal | Physics in Medicine & Biology |
| Issue Number | 5 |
| Volume Number | 42 |
| Language | English |
| Publisher | IOP Publishing |
| Publisher Date | 1997-05-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Physics in Medicine & Biology Pharmacology and Pharmacy Diagnostic Information Fluorescence Imaging Imaging for Tissue Tissue Diagnostics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging Radiological and Ultrasound Technology |
