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What pulmonologists think about the asthma–COPD overlap syndrome

Content Provider	Scilit
Author	Miravitlles, Marc Alcazar, Bernardino Alvarez-Gutierrez, Fracisco Bazús, Teresa Calle, Myriam Casanova, Ciro Cisneros, Carolina De-Torres, Juan Entrenas, Luis Esteban, Cristóbal García-Sidro, Patricia Cosio, Borja G. Huerta, Arturo Iriberri, Milagros Izquierdo, José Luis López-Viña, Antolin López-Campos, José Luis Martinez-Moragon, Eva de Llano, Luis Pérez Perpiñá, Miguel Ros, José Serrano, José Soler-Cataluña, Juan José Torrego, Alfons Plaza, Vicente Urrutia, Isabel
Copyright Year	2015
Description	Journal: International journal of chronic obstructive pulmonary disease Some patients with COPD may share characteristics of asthma; this is the so-called asthma–COPD overlap syndrome (ACOS). There are no universally accepted criteria for ACOS, and most treatments for asthma and COPD have not been adequately tested in this population. We performed a survey among pulmonology specialists in asthma and COPD aimed at collecting their opinions about ACOS and their attitudes in regard to some case scenarios of ACOS patients. The participants answered a structured questionnaire and attended a face-to-face meeting with the Metaplan methodology to discuss different aspects of ACOS. A total of 26 pulmonologists with a mean age of 49.7 years participated in the survey (13 specialists in asthma and 13 in COPD). Among these, 84.6% recognized the existence of ACOS and stated that a mean of 12.6% of their patients might have this syndrome. In addition, 80.8% agreed that the diagnostic criteria for ACOS are not yet well defined. The most frequently mentioned characteristics of ACOS were a history of asthma (88.5%), significant smoking exposure (73.1%), and postbronchodilator forced expiratory volume in 1 second/forced vital capacity <0.7 (69.2%). The most accepted diagnostic criteria were eosinophilia in sputum (80.8%), a very positive bronchodilator test (69.2%), and a history of asthma before 40 years of age (65.4%). Up to 96.2% agreed that first-line treatment for ACOS was the combination of a long-acting β2-agonist and inhaled steroid, with a long-acting antimuscarinic agent (triple therapy) for severe ACOS. Most Spanish specialists in asthma and COPD agree that ACOS exists, but the diagnostic criteria are not yet well defined. A previous history of asthma, smoking, and not fully reversible airflow limitation are considered the main characteristics of ACOS, with the most accepted first-line treatment being long-acting β2-agonist/inhaled corticosteroids.
Related Links	https://www.dovepress.com/getfile.php?fileID=25971 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507793/pdf
Ending Page	1330
Page Count	10
Starting Page	1321
ISSN	11769106
e-ISSN	11782005
DOI	10.2147/copd.s88667
Journal	International journal of chronic obstructive pulmonary disease
Volume Number	10
Language	English
Publisher	Informa UK Limited
Publisher Date	2015-07-01
Access Restriction	Open
Subject Keyword	Journal: International journal of chronic obstructive pulmonary disease
Content Type	Text
Subject	Pulmonary and Respiratory Medicine Public Health, Environmental and Occupational Health Health Policy

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