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Immunovirotherapy for the treatment of glioblastoma
| Content Provider | Scilit |
|---|---|
| Author | Cheema, Tooba A. Fecci, Peter Ning, Jianfang Rabkin, Samuel D. |
| Copyright Year | 2014 |
| Description | Journal: OncoImmunology We have recently described a new murine model of glioblastoma, generated by the implantation of syngeneic glioblastoma stem cells into immunocompetent mice, that recapitulates the salient histopathological and immunological features of the human disease. We employed this model to demonstrate the multifaceted activity of an oncolytic herpes simplex virus genetically modified to express interleukin-12, G47∆-IL12. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929360/pdf |
| e-ISSN | 2162402X |
| DOI | 10.4161/onci.27218 |
| Journal | OncoImmunology |
| Issue Number | 1 |
| Volume Number | 3 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2014-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: OncoImmunology Cancer Stem Cells Herpes Simplex Virus Interleukin-12 Oncolytic Virus |
| Content Type | Text |