NDLI: Orbital rhabdomyosarcoma fifty-seven years after radiotherapy for retinoblastoma

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Orbital rhabdomyosarcoma fifty-seven years after radiotherapy for retinoblastoma

Content Provider	Scilit
Author	Wilson, Martin C. Shields, Jerry A. Shields, Carol L. Litzky, Leslie
Copyright Year	1996
Description	Journal: Orbit A 58-year-old man developed a left orbital mass 57 years after bilateral enucleation and external beam radiotherapy for bilateral sporadic retinoblastoma. Eighteen years earlier, the patient had a basal cell carcinoma successfully excised from the same area. Orbital computed tomography revealed an infiltrative soft tissue mass measuring 50 ± 40 ± 15 mm involving the left medial orbit, left ethmoid sinus and the cribriform plate. An incisional biopsy was performed, and the lesion proved to be a poorly differentiated rhabdomyosarcoma of alveolar cell type. Despite aggressive chemotherapy, intracranial extension progressed and the patient expired. Late second malignancy following irradiated and non-irradiated retinoblastoma has been documented to occur even up to 54 years after retinoblastoma diagnosis. The 57-year interval between retinoblastoma and second cancer highlights this phenomenon and emphasizes the need for long term medical care of these patients.
Related Links	https://www.tandfonline.com/doi/pdf/10.3109/01676839609150075
ISSN	01676830
e-ISSN	17445108
DOI	10.3109/01676839609150075
Journal	Orbit
Issue Number	2
Volume Number	15
Language	English
Publisher	Informa UK Limited
Publisher Date	1996-01-01
Access Restriction	Open
Subject Keyword	Journal: Orbit Rhabdomyosarcoma Retinoblastoma Second Tumors
Content Type	Text
Subject	Ophthalmology

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