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On the antigenic relationship between the αA and αB subunits of α-crystallin in bovine lens
| Content Provider | Scilit |
|---|---|
| Author | Butler, Debra M. Augusteyn, Robert C. |
| Copyright Year | 1986 |
| Description | Journal: Current Eye Research The immunochemical reactivities of the αA and αB subunits from bovine α-crystallin have been compared using 5 monoclonal antibodies and 2 polyvalent antisera. Each subunit bound the same maximum amount of antibody, regardless of its source, and each subunit was able to completely displace α-crystallin from its antibodies. One monoclonal antibody (463–122) and mouse anti-αB polyclonal antiserum bound equally well to the two subunits; with the other monoclonal antibodies and an anti α-crystallin antiserum, the affinities for the αA chains were about 103 fold higher than those for the αB chains. These observations indicate that the αA and αB subunits of bovine α-crystallin share several similar, but not necessarily identical, cross-reacting antigenic determinants. The reasons for the differences between these observations and those of other investigators are discussed. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/02713688609020047 |
| Ending Page | 229 |
| Page Count | 5 |
| Starting Page | 225 |
| ISSN | 02713683 |
| e-ISSN | 14602202 |
| DOI | 10.3109/02713688609020047 |
| Journal | Current Eye Research |
| Issue Number | 3 |
| Volume Number | 5 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1986-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Current Eye Research Antigenic Relationship |
| Content Type | Text |
| Subject | Ophthalmology Sensory Systems Cellular and Molecular Neuroscience |
