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Lignin: Drug/Gene Delivery and Tissue Engineering Applications
| Content Provider | Scilit |
|---|---|
| Author | Kumar, Raj Butreddy, Arun Kommineni, Nagavendra Reddy, Pulikanti Guruprasad Bunekar, Naveen Sarkar, Chandrani Dutt, Sunil Mishra, Vivek K. Aadil, Keshaw Ram Mishra, Yogendra Kumar Oupicky, David Kaushik, Ajeet |
| Copyright Year | 2021 |
| Description | Journal: International Journal of Nanomedicine Abstract: Lignin is an abundant renewable natural biopolymer. Moreover, a significant development in lignin pretreatment and processing technologies has opened a new window to explore lignin and lignin-based bionanomaterials. In the last decade, lignin has been widely explored in different applications such as drug and gene delivery, tissue engineering, food science, water purification, biofuels, environmental, pharmaceuticals, nutraceutical, catalysis, and other interesting low-value-added energy applications. The complex nature and antioxidant, antimicrobial, and biocompatibility of lignin attracted its use in various biomedical applications because of ease of functionalization, availability of diverse functional sites, tunable physicochemical and mechanical properties. In addition to it, its diverse properties such as reactivity towards oxygen radical, metal chelation, renewable nature, biodegradability, favorable interaction with cells, nature to mimic the extracellular environment, and ease of nanoparticles preparation make it a very interesting material for biomedical use. Tremendous progress has been made in drug delivery and tissue engineering in recent years. However, still, it remains challenging to identify an ideal and compatible nanomaterial for biomedical applications. In this review, recent progress of lignin towards biomedical applications especially in drug delivery and in tissue engineering along with challenges, future possibilities have been comprehensively reviewed. |
| Related Links | https://www.dovepress.com/getfile.php?fileID=68043 |
| Ending Page | 2441 |
| Page Count | 23 |
| Starting Page | 2419 |
| e-ISSN | 11782013 |
| DOI | 10.2147/ijn.s303462 |
| Journal | International Journal of Nanomedicine |
| Volume Number | ume 16 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2021-03-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: International Journal of Nanomedicine Biomedical Engineering Drug Delivery Nano-biosystem Nanomedicine Tissue Engineering |
| Content Type | Text |