NDLI: PRL-3: A phosphatase for metastasis?

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PRL-3: A phosphatase for metastasis?

Content Provider	Scilit
Author	Sager, Jason A. Benvenuti, Silvia Bardelli, Alberto
Copyright Year	2004
Description	Journal: Cancer Biology & Therapy The PRL-3 phosphatase has joined the cancer arena very recently but is rapidly gaining interest both as a putative prognostic factor and as a therapeutic target for metastatic tumors. In this issue Guo and colleagues provide another key piece of information by showing that the catalytic activity of PRL-3 is required for experimental metastasis formation in mouse models. Here we summarize the current knowledge and discuss what remains to be done before PRL-3 could be considered as a target for diagnostics or therapeutics in the clinical setting of human cancer.
Related Links	https://www.tandfonline.com/doi/pdf/10.4161/cbt.3.10.1115?needAccess=true https://www.landesbioscience.com/journals/cbt/sager3-10.pdf
Ending Page	953
Page Count	2
Starting Page	952
ISSN	15384047
e-ISSN	15558576
DOI	10.4161/cbt.3.10.1115
Journal	Cancer Biology & Therapy
Issue Number	10
Volume Number	3
Language	English
Publisher	Informa UK Limited
Publisher Date	2004-10-27
Access Restriction	Open
Subject Keyword	Journal: Cancer Biology & Therapy Biochemistry and Molecular Biology Medical Laboratory Technology Experimental
Content Type	Text
Resource Type	Article
Subject	Cancer Research Pharmacology Molecular Medicine Oncology

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