NDLI: Longitudinal study of the diffusion tensor imaging properties of the corpus callosum in acute and chronic diffuse axonal injury

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Longitudinal study of the diffusion tensor imaging properties of the corpus callosum in acute and chronic diffuse axonal injury

Content Provider	Scilit
Author	Ljungqvist, Johan Nilsson, Daniel Ljungberg, Maria Sörbo, Ann Esbjörnsson, Eva Eriksson-Ritzén, Catherine Skoglund, Thomas
Copyright Year	2011
Description	Journal: Brain Injury Magnetic resonance diffusion tensor imaging (MR-DTI) is used increasingly to detect diffuse axonal injury (DAI) after traumatic brain injury (TBI). The primary objective was to investigate the changes in the diffusion properties of the corpus callosum in the acute phase and 6 months after TBI and to examine the correlation between DTI parameters and clinical outcome. Longitudinal prospective study. MR-DTI was performed in eight patients with suspected DAI within 11 days and at 6 months post-injury. Six controls were also examined. Fractional anisotropy (FA), trace and parallel and perpendicular diffusivity of the corpus callosum were analysed. The main outcome was the extended Glasgow Outcome Scale score, assessed at 6 months. A significant reduction in FA in the corpus callosum was seen in the acute phase in patients compared with the healthy controls. There was no significant change in the parallel or perpendicular eigenvalues or trace. At 6 months, a significant reduction in FA and a significant increase in trace and perpendicular eigenvalues were noticed compared with controls. The diffusion properties of the corpus callosum correlated with clinical outcome in this longitudinal investigation.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/02699052.2011.558038
Ending Page	378
Page Count	9
Starting Page	370
ISSN	02699052
e-ISSN	1362301X
DOI	10.3109/02699052.2011.558038
Journal	Brain Injury
Issue Number	4
Volume Number	25
Language	English
Publisher	Informa UK Limited
Publisher Date	2011-02-11
Access Restriction	Open
Subject Keyword	Journal: Brain Injury Neuroimaging Longitudinal Corpus Callosum
Content Type	Text
Subject	Neuroscience Developmental and Educational Psychology Neurology (clinical)

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