NDLI: A delayed injection-site reaction in a patient receiving extended-release naltrexone.

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A delayed injection-site reaction in a patient receiving extended-release naltrexone.

Content Provider	Scilit
Author	Ahamad, Keith Korthuis, P. Todd Lum, Paula J. Johnson, Cheyenne Wood, Evan
Copyright Year	2015
Description	Journal: Substance Abuse Background: Pharmacotherapy, such as oral naltrexone, has proven effective in treating alcohol use disorder, although medication adherence has presented challenges. Although a formulation of extended-release naltrexone for intramuscular injection has been developed to counter daily adherence issues, injection-site reactions can occur within days of depot injection. Case: The authors report a case of an individual with alcohol use disorder who had a previously undescribed delayed injection-site reaction that occurred 11 days after injection. Subsequent challenge with the medication resulted in recurrence of the reaction. Discussion: Although extended-release naltrexone is generally well tolerated, injection-site reactions can complicate treatment and can appear more than 10 days after medication administration.
Related Links	https://cloudfront.escholarship.org/dist/prd/content/qt54x1s560/qt54x1s560.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266530/pdf
ISSN	08897077
e-ISSN	15470164
DOI	10.1080/08897077.2016.1138919
Journal	Substance Abuse
Issue Number	2
Volume Number	37
Language	English
Publisher	Informa UK Limited
Publisher Date	2015-10-09
Access Restriction	Open
Subject Keyword	Journal: Substance Abuse Clinical Psychology Substance Abuse Alcohol Use Disorder Extended-release Naltrexone Injection-site Reaction
Content Type	Text
Subject	Psychiatry and Mental Health

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