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Cytophotometric Estimation of Cell Proliferation in Breast Cancer: Correlation to the clinical course during long-term follow-up
| Content Provider | Scilit |
|---|---|
| Author | Hatschek, T. Bjelkenkrantz, K. Garstensen, J. Nordenskjöld, B. Nordin, B. Stål, O. Stenkvist, B. |
| Copyright Year | 1989 |
| Description | Journal: Acta Oncologica Tumours from 117 patients with breast cancer operated during a 5-month period 1975-1976 were investigated by absorbance scanning cytophotometry. The relations of these data to breast cancer recurrence and death during a follow-up period of 8.5 years were analysed using Cox's proportional hazards model. When individually tested, nodal status, grade of malignancy and high rates of proliferation, as indicated by cells in S-phase, were statistically significant predictors of the clinical outcome. The risk ratio associated with S-phase decreased significantly over time from primary treatment. No significant relation was found between DNA-ploidy or tumour size and the clinical course. In the multivariate analysis, based on 76 patients, nodal status alone was a significant prognostic factor. |
| Related Links | https://www.tandfonline.com/doi/pdf/10.3109/02841868909092311?needAccess=true |
| Ending Page | 806 |
| Page Count | 6 |
| Starting Page | 801 |
| ISSN | 0284186X |
| e-ISSN | 1651226X |
| DOI | 10.3109/02841868909092311 |
| Journal | Acta Oncologica |
| Issue Number | 6 |
| Volume Number | 28 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1989-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Acta Oncologica Radiology, Nuclear Medicine and Imaging Multivariate Analysis Breast Cancer Proliferation Clinical Course |
| Content Type | Text |
| Subject | Radiology, Nuclear Medicine and Imaging Hematology Oncology |
