NDLI: Biology of $CD34^{+}CD38^{-}$Cells in Lymphohematopoiesis

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Biology of $CD34^{+}CD38^{-}$Cells in Lymphohematopoiesis

Content Provider	Scilit
Author	Novelli, Enrico M. Ramirez, Manuel Civin, Curt I.
Copyright Year	1998
Description	Journal: Leukemia & Lymphoma Since the discovery of the CD34 stem/progenitor cell antigen, considerable progress has been made in further purifying human lymphohematopoietic stem cells (HSC). These studies have identified a number of antigens which can be targeted to subfractionate the $CD34^{+}$ cell population. In particular, several lines of evidence suggest that the rare $CD38^{-}$ subpopulation of $CD34^{+}$ cells may be enriched in HSC. This review briefly summarizes relevant knowledge concerning the CD38 molecule and the results of in vitro and in vivo studies of $CD34+38^{-}$ cells. Possible clinical uses for purified CD34+38” cells are outlined.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/10428199809059221
Ending Page	293
Page Count	9
Starting Page	285
ISSN	10428194
e-ISSN	10292403
DOI	10.3109/10428199809059221
Journal	Leukemia & Lymphoma
Issue Number	3-4
Volume Number	31
Language	English
Publisher	Informa UK Limited
Publisher Date	1998-01-01
Access Restriction	Open
Subject Keyword	Journal: Leukemia & Lymphoma Cell Tissue Engineering Lymphohematopoiesis Stem/progenitor Subpopulation
Content Type	Text
Subject	Hematology Cancer Research Oncology

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