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Craving predicts opioid use in opioid-dependent patients initiating buprenorphine treatment: A longitudinal study
| Content Provider | Scilit |
|---|---|
| Author | Tsui, Judith I. Anderson, Bradley J. Strong, David R. Stein, Michael D. |
| Copyright Year | 2014 |
| Description | Journal: The American journal of drug and alcohol abuse Background: Few studies have assessed associations between craving and subsequent opioid use. We prospectively evaluated the relative utility of two craving questionnaires to predict opioid use among opioid-dependent patients in outpatient treatment. Method: Opioid-dependent patients (n = 147) initiating buprenorphine treatment were assessed every two weeks for 3 months. Craving was measured using the: (1) Desires for Drug Questionnaire (DDQ) and (2) Penn Alcohol-Craving Scale adapted for opioid craving (PCS). Multi-level logistic regression models estimated the effects of craving on the likelihood of opioid use. Craving assessed at time t was entered as a time-varying predictor of opioid use at time t + 1. Results: Craving scores plateaued at approximately 2 weeks after initiation of buprenorphine. In adjusted regression models, a 1-point increase in PCS scores (on a 7-point scale) was associated with a significant increase in the odds of opioid use at the subsequent assessment (OR = 1.27, 95% CI 1.08; 1.49, p < 0.01). The odds of opioid use at the subsequent follow-up assessment increased significantly as DDQ desire and intention scores increased (OR = 1.25, 95%CI 1.03; 1.51, p < 0.05), but was not significantly associated with DDQ negative reinforcement (OR = 1.01, 95%CI 0.88; 1.17, p > 0.05) or DDQ control (OR = 0.97, 95%CI 0.85; 1.11, p > 0.05) scores. Conclusion: Self-reported craving for opioids was modestly associated with subsequent relapse to opioid use among a cohort of patients treated with buprenorphine. Assessment of craving may provide clinical utility in predicting relapse among treated opioid-dependent patients. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868341/pdf https://www.tandfonline.com/doi/pdf/10.3109/00952990.2013.848875 |
| Ending Page | 169 |
| Page Count | 7 |
| Starting Page | 163 |
| ISSN | 00952990 |
| e-ISSN | 10979891 |
| DOI | 10.3109/00952990.2013.848875 |
| Journal | The American journal of drug and alcohol abuse |
| Issue Number | 2 |
| Volume Number | 40 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2014-03-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: The American journal of drug and alcohol abuse Substance Abuse Buprenorphine Opioid Dependence |
| Content Type | Text |
| Subject | Clinical Psychology Psychiatry and Mental Health |
