NDLI: Epidermal barrier dysfunction in atopic dermatitis

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Epidermal barrier dysfunction in atopic dermatitis

Content Provider	Scilit
Copyright Year	2008
Description	Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with cutaneous hyper-reactivity to environmental triggers that are innocuous to normal, non-atopic individuals.1 Major contributors to this hyperactivity are the many changes in the cutaneous and systemic immune responses in individuals with AD.2 One example is the production of raised levels of total serum immunoglobulin IgE and specific IgE to common allergens.3 However, the link between AD and allergen-specific IgE remains hotly debated.4 A recent systematic review revealed that the association with raised IgE was much lower in children with mild to moderate AD than in children with severe disease.3It has been postulated that the non-allergic, intrinsic dermatitis could be a pure, transitional form of AD.5 Book Name: Textbook of Atopic Dermatitis
Related Links	https://www.taylorfrancis.com/chapters/edit/10.3109/9780203091449-8/epidermal-barrier-dysfunction-atopic-dermatitis-michael-cork-simon-danby-yiannis-vasilopoulos-manar-moustafa-alice-macgowan-jibu-varghese-gordon-duff-rachid-tazi-ahnini-simon-ward
Ending Page	70
Page Count	24
Starting Page	47
DOI	10.3109/9780203091449-8
Language	English
Publisher	Informa UK Limited
Publisher Date	2008-05-01
Access Restriction	Open
Subject Keyword	Book Name: Textbook of Atopic Dermatitis Atopic Dermatitis Specific Ige Transitional Form Cutaneous Hyper
Content Type	Text
Resource Type	Chapter

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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