NDLI: The Structure of Human MHC Class II Genes

Content Provider	Scilit
Author	Rask, Lars Jonsson, Ann-Kristin Svensson, Ann-Cathrin Gustafsson, Kenth Andersson, Leif
Copyright Year	1991
Description	Journal: Autoimmunity The class II molecules of the human major histocompatibility complex bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response. A salient feature of the class II molecules is their polymorphism. It has been shown that some autoimmune diseases are associated with certain class II alleles. This article reviews the basic structural features of class II molecules, and the genes encoding them as well as mechanisms governing the development of their extraordinary polymorphism.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/08916939108997111
Ending Page	244
Page Count	8
Starting Page	237
ISSN	08916934
e-ISSN	1607842X
DOI	10.3109/08916939108997111
Journal	Autoimmunity
Issue Number	3
Volume Number	8
Language	English
Publisher	Informa UK Limited
Publisher Date	1991-01-01
Access Restriction	Open
Subject Keyword	Journal: Autoimmunity Polymorphism
Content Type	Text
Subject	Immunology and Allergy Immunology

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