NDLI: Synthesis of both enantiomers of lycoperdic acid, an unusual mushroom-derived amino acid

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Synthesis of both enantiomers of lycoperdic acid, an unusual mushroom-derived amino acid

Content Provider	Scilit
Author	Katsuta, Ryo Ishiuchi, Ryutaro Kunisawa, Mikiko Yajima, Arata Ishigami, Ken Nukada, Tomoo
Copyright Year	2021
Description	Journal: Bioscience, Biotechnology, and Biochemistry An efficient synthesis of both enantiomers of lycoperdic acid, a 4-hydroxyglutamic acid derivative from edible mushroom Lycoperdon perlatum, was achieved from a chiral aminoalcohol. The key steps were a stereoselective introduction of a $C_{3}$ unit into a bicyclic ketone and oxidative cleavage of a cyclic vicinal diol into a dicarboxylic acid. This report provides the first synthesis of (−)-lycoperdic acid.
Related Links	https://academic.oup.com/bbb/article-pdf/85/1/154/35480572/zbaa027.pdf
Ending Page	159
Page Count	6
Starting Page	154
ISSN	09168451
e-ISSN	13476947
DOI	10.1093/bbb/zbaa027
Journal	Bioscience, Biotechnology, and Biochemistry
Issue Number	1
Volume Number	85
Language	English
Publisher	Informa UK Limited
Publisher Date	2021-01-07
Access Restriction	Open
Subject Keyword	Journal: Bioscience, Biotechnology, and Biochemistry Organic Chemistry Unusual Amino Acid Glutamic Acid Lycoperdic Acid
Content Type	Text
Subject	Organic Chemistry Medicine Analytical Chemistry Molecular Biology Biochemistry Applied Microbiology and Biotechnology Biotechnology

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