NDLI: The Laboratory Rat

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The Laboratory Rat

Content Provider	Scilit
Author	Everds, Nancy E. Ramaiah, Lila
Copyright Year	2017
Description	The laboratory rat is one of the most extensively used animal models in biomedical research. The modern laboratory rat is considered to be derived from naturally occurring albino mutants of the wild Norway rat (Rattus norvegicus), which originated in China but is now found on all continents except Antarctica. Albino Norway rats were bred in the nineteenth century as show animals and eventually became utilized in research laboratories. Phenotypic differences between rats of different genetic backgrounds can be quite useful when modeling particular diseases. However, these differences also have a considerable impact on many research endpoints. In rats, urine may be collected by free catch, timed collection into metabolic cages, and cystocentesis, catheterization, or cystotomy at necropsy. Clinical chemistry parameters that are consistently higher in males compared to female rats are serum ALP and triglycerides, and urine protein and ketones. Book Name: The Clinical Chemistry of Laboratory Animals
Related Links	https://api.taylorfrancis.com/content/chapters/edit/download?identifierName=doi&identifierValue=10.1201/9781315155807-2&type=chapterpdf
Ending Page	78
Page Count	46
Starting Page	33
DOI	10.1201/9781315155807-2
Language	English
Publisher	Informa UK Limited
Publisher Date	2017-10-18
Access Restriction	Open
Subject Keyword	Book Name: The Clinical Chemistry of Laboratory Animals History and Philosophy of Science Laboratory Rat Models Albino Protein Animal Norway Rat Rats of Different
Content Type	Text
Resource Type	Chapter

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