NDLI: Potential role of lampalizumab for treatment of geographic atrophy

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Potential role of lampalizumab for treatment of geographic atrophy

Content Provider	Scilit
Author	Do, Diana Rhoades, William Dickson, Drew
Copyright Year	2015
Description	Journal: Clinical Ophthalmology Potential role of lampalizumab for treatment of geographic atrophy William Rhoades, Drew Dickson, Diana V Do Truhlsen Eye Institute, Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, NE, USA The purpose of this article is to review the pathways underlying age-related macular degeneration and potential therapeutic targets, focusing on the complement pathway and the recent MAHALO Phase II trial of the investigational drug lampalizumab. This trial was the first to have shown positive results for the treatment of geographic atrophy in age-related macular degeneration. It has potential as a future treatment, and is currently undergoing a Phase III trial. Keywords: age-related macular degeneration, complement inhibition, AMD
Related Links	https://www.dovepress.com/getfile.php?fileID=25633 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468985/pdf http://www.dovepress.com/getfile.php?fileID=25633
Ending Page	1056
Page Count	8
Starting Page	1049
ISSN	11775467
e-ISSN	11775483
DOI	10.2147/opth.s59725
Journal	Clinical Ophthalmology
Volume Number	ume 9
Language	English
Publisher	Informa UK Limited
Publisher Date	2015-06-01
Access Restriction	Open
Subject Keyword	Journal: Clinical Ophthalmology Agricultural Engineering Age-related Macular Degeneration Complement Inhibition
Content Type	Text
Subject	Ophthalmology

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