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Parenteral Formulations: Local Injection Site Reaction and Muscle Tolerance
| Content Provider | Scilit |
|---|---|
| Copyright Year | 2013 |
| Description | Due to the invasive nature of parenteral administration, and direct and rapid systemic exposure of the administered formulation, parenteral products are required to conform to strict guidelines of sterility, lack of foreign matter, and lack of pyrogenicity. This entry first provides a brief introduction to the types of local injection site and tissue reactions, then moves to a discussion of their impact, mechanisms for poor toleration, and various models used to asses injection site reactions. Additionally, this entry attempts to relation formulation composition, properties, and dose administration techniques that impact injection site reactions as a means to guide pharmaceutical scientists engaged in development of parenteral drug products. Book Name: Encyclopedia of Pharmaceutical Science and Technology, Fourth Edition |
| Related Links | https://api.taylorfrancis.com/content/chapters/edit/download?identifierName=doi&identifierValue=10.1081/E-EPT4-120050317&type=chapterpdf |
| Ending Page | 2450 |
| Page Count | 20 |
| Starting Page | 2431 |
| DOI | 10.1081/e-ept4-120050317 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2013-07-01 |
| Access Restriction | Open |
| Subject Keyword | Book Name: Encyclopedia of Pharmaceutical Science and Technology, Fourth Edition Crystallography Tolerance Formulation Conform Administration Injection Site Reactions Parenteral Models |
| Content Type | Text |
| Resource Type | Chapter |