NDLI: Localization of sex hormone-binding globulin mRNA expression in human uterine endometrium

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Localization of sex hormone-binding globulin mRNA expression in human uterine endometrium

Content Provider	Scilit
Author	Misao, R. Fujimoto, J. Itoh, N. Nakanishi, Y. Tamaya, T.
Copyright Year	1997
Description	Journal: Gynecological Endocrinology To identify the dominant cell of sex hormone-binding globulin (SHBG) synthesis in human uterine endometrium, we investigated the expression of endometrial SHBG mRNA using Northern blot and in situ hybridization analyses. Expression of a single dominant SHBG mRNA was detected in uterine endometrium using Northern blot analysis. Additionally, SHBG mRNA expression was demonstrated by in situ hybridization in the glandular epithelial cells of the endometrium, but not in the stromal cells. Therefore, in the endometrial glandular epithelial cells, SHBG might be involved in the intracellular steroidal action, but not in the endometrial stromal cells. The SHBG-mediated effects on the endometrium appear to be heterogeneous.
Related Links	https://www.tandfonline.com/doi/pdf/10.3109/09513599709152308
Ending Page	4
Page Count	4
Starting Page	1
ISSN	09513590
e-ISSN	14730766
DOI	10.3109/09513599709152308
Journal	Gynecological Endocrinology
Issue Number	1
Volume Number	11
Language	English
Publisher	Informa UK Limited
Publisher Date	1997-01-01
Access Restriction	Open
Subject Keyword	Journal: Gynecological Endocrinology Reproductive Biology Sex Hormone-binding Globulin Messenger Rna Uterine Endometrium In Situ Hybridization
Content Type	Text
Subject	Endocrinology, Diabetes and Metabolism Endocrinology Obstetrics and Gynecology

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