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Inflammatory Association with Childhood Obstructive Sleep Apnea Syndrome
| Content Provider | Scilit |
|---|---|
| Copyright Year | 2008 |
| Description | In 1877, W.H. Broadbent, a British physician, provided one of the earliestdescriptions of obstructive sleep apnea syndrome (OSAS) (1) in the journalLancet. He characterized the condition as failure of inspiration to overcome theresistance in the pharynx leading to snoring and periods of perfect silence duringseveral respiratory periods. It was not until the mid to late 1900s that the highprevalence of this condition in children and adults was recognized by themedical community. The mounting knowledge of OSAS and of its pathogenesisevolved over time as we began learning about the association of the disorderwith serious adverse health outcomes. Significant progress has been made overthe last two decades in our understanding of the mechanisms mediating adversehealth outcomes due to OSAS. Such progress was supported by the technologicaladvances in the study of sleep, in the continuous monitoring of ventilatoryparameters, and finally in the revolution in molecular techniques. Specifically,these advances supported the investigation of the inflammatory and metabolicdisease mechanisms in children and adults with OSAS. Book Name: Sleep and Breathing in Children |
| Related Links | https://www.taylorfrancis.com/chapters/edit/10.3109/9781420060836-27/inflammatory-association-childhood-obstructive-sleep-apnea-syndrome-raouf-amin |
| Ending Page | 538 |
| Page Count | 18 |
| Starting Page | 521 |
| DOI | 10.3109/9781420060836-27 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2008-02-19 |
| Access Restriction | Open |
| Subject Keyword | Book Name: Sleep and Breathing in Children Respiratory System Apnea Syndrome Obstructive Sleep |
| Content Type | Text |
| Resource Type | Chapter |
