NDLI: Chromatographic Analysis of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD)

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Chromatographic Analysis of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD)

Content Provider	Scilit
Author	Shibamoto, Takayuki
Copyright Year	2021
Description	Dioxin, in particular 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD), is the most potent man-made carcinogen. Dioxin contamination in the environment has received much attention, not only from environmental chemists but also from the public, because of its potent carcinogenicity. Since Tswett invented column chromatography (CC) in 1906, it has been widely used to separate organic materials form complex matrices. There are several excellent review articles containing CC cleanup methods. The CC cleanup methods included an extrelut column, silica gel, florisil column, and an alumina column. Since the invention of gas chromatography (GC) in the early 1950s, determination of trace contaminants in various matrices became possible. Once adequate cleanup is accomplished, high-resolution and highly sensitive GC or gas chromatography/mass spectrometry (GC/MS) can achieve satisfactory analysis of TCDDs. A normal-phase high-performance liquid chromatography was used to fractionate complex mixtures into several simple fractions, and then further analysis of TCDDs was conducted using GC/MS. Book Name: Chromatographic Analysis of Environmental and Food Toxicants
Related Links	https://api.taylorfrancis.com/content/chapters/edit/download?identifierName=doi&identifierValue=10.1201/9781003208808-7&type=chapterpdf
Ending Page	228
Page Count	16
Starting Page	213
DOI	10.1201/9781003208808-7
Language	English
Publisher	Informa UK Limited
Publisher Date	2021-05-01
Access Restriction	Open
Subject Keyword	Book Name: Chromatographic Analysis of Environmental and Food Toxicants Analytical Chemistry Chromatography Contaminants Dioxin Column Tetrachlorodibenzo Carcinogen Cleanup
Content Type	Text
Resource Type	Chapter

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