NDLI: Implications of Neurotrophin Supported Auditory Neuron Survival for Maintenance of the Tonotopic Organization of the Central Auditory Pathway

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Implications of Neurotrophin Supported Auditory Neuron Survival for Maintenance of the Tonotopic Organization of the Central Auditory Pathway

Content Provider	Scilit
Author	Reser, David H. Water, Thomas R. Van De
Copyright Year	1997
Description	Journal: Acta Oto-Laryngologica Recent experiments have demonstrated the effectiveness of members of the neurotrophin family of growth factors in supporting the survival of primary auditory neurons following ototoxic trauma. In this report, we examined the implications of these results in light of current knowledge about activity dependent central nervous system reorganization. We suggest that the use of trophic factors in conjunction with patterned stimulation of afferent nerve fibers could preserve the majority of the tonotopic arrangement of the central pathway. We propose experiments to test the effects of NT-3 induced neuron survival on the organization of primary auditory cortex.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/00016489709117779
Ending Page	243
Page Count	5
Starting Page	239
ISSN	00016489
e-ISSN	16512251
DOI	10.3109/00016489709117779
Journal	Acta Oto-Laryngologica
Issue Number	2
Volume Number	117
Language	English
Publisher	Informa UK Limited
Publisher Date	1997-01-01
Access Restriction	Open
Subject Keyword	Journal: Acta Oto-Laryngologica Neurosciences Auditory Pathway Neurotrophin Supported Supported Auditory Central Auditory Tonotopic Organization Auditory Neuron
Content Type	Text
Subject	Otorhinolaryngology

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