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Electrospun Matrices for Biomedical Applications—Recent Advances
| Content Provider | Scilit |
|---|---|
| Copyright Year | 2016 |
| Description | Electrospinning is a unique, versatile, and facile approach for engineering nanofibrous scaffolds with characteristic micro to nanoscale topography and high porosity similar to the natural extracellular matrix (ECM). These nanofibrous matrices influence cellular activities both in vitro and in vivo. Biodegradable polymers used for the electrospinning can be of synthetic (PCL, PVA, PLA, PLGA, PVP, etc.) or natural (alginate, chitosan, collagen, elastin, fibrinogen, gelatin, keratin, etc.) origin. High surface to volume ratio and porous nature of the electrospun scaffolds help in the attachment of cells and incorporation of proteins, DNA, RNA, and drugs ranging from antibiotics to anticancer agents. Thus, they find promising applications in drug delivery, tissue engineering, wound dressing, and in other areas. In this chapter, electrospinning method for the generation of nanofibrous scaffolds and its important biomedical applications are reviewed. Book Name: Nanomedicine and Tissue Engineering |
| Related Links | https://api.taylorfrancis.com/content/chapters/edit/download?identifierName=doi&identifierValue=10.1201/b19867-16&type=chapterpdf |
| Ending Page | 416 |
| Page Count | 26 |
| Starting Page | 391 |
| DOI | 10.1201/b19867-16 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2016-03-30 |
| Access Restriction | Open |
| Subject Keyword | Book Name: Nanomedicine and Tissue Engineering Electrospinning Matrices Proteins Electrospun Biomedical Engineering Applications Nanofibrous Scaffolds |
| Content Type | Text |
| Resource Type | Chapter |