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Tumor-infiltrating follicular helper T cells: The new kids on the block
| Content Provider | Scilit |
|---|---|
| Author | Gu-Trantien, Chunyan Willard-Gallo, Karen |
| Copyright Year | 2013 |
| Description | Journal: OncoImmunology By analyzing $CD4^{+}$ lymphocytes in human breast carcinomas, we have recently uncovered the presence of follicular helper T cells in lesions exhibiting an extensive immune infiltrate. The presence of these specialized $CD4^{+}$ T cells, which localize to the germinal centers of peritumoral tertiary lymphoid structures found in extensively infiltrated neoplastic lesions, predicts improved disease outcome among breast carcinoma patients. |
| Related Links | https://www.tandfonline.com/doi/pdf/10.4161/onci.26066?needAccess=true https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825729/pdf |
| e-ISSN | 2162402X |
| DOI | 10.4161/onci.26066 |
| Journal | OncoImmunology |
| Issue Number | 10 |
| Volume Number | 2 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2013-10-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: OncoImmunology Research and Experimental Medicine Anticancer Immunity Breast Cancer Follicular Helper T Cells Tertiary Lymphoid Structures Tumor-infiltrating Lymphocytes |
| Content Type | Text |